john simpson

Cholesterol reduction: A look at the evidence

Blog Post created by john simpson on Feb 22, 2011 (Montpellier, France: 37,500  monthly unique users)
"Cholesterol reduction: A look at the  evidence"
February 15


In the second part of our special focus on heart health,  NutraIngredients examines the science that backs up the health benefits of ‘the  big four’ cholesterol reducing ingredients: phytosterols, omega-3s, beta-glucan,  and soy protein... The Food and Drug Administration (FDA) heart health claim for  soy protein established in 1999 states that "25 grams of soy protein a day, as  part of a diet low in saturated fat and cholesterol, may reduce the risk of  heart disease." Currently, 11 other countries have approved health claims for  soy protein's potential to lower blood cholesterol and lower the risk of  coronary heart disease. However, recently the European Food Safety Authority  (EFSA) issued a negative opinion to a health claim submission linking soy  protein and reduced cholesterol – stating that there was not enough evidence of  causation to approve a claim in Europe. A 2008 study suggested that the  cholesterol-lowering effects of soy protein may by located in the liver. The  study, published in the Journal of Agricultural and Food  Chemistry, reported that soybean protein was found to stimulate the  low-density lipoprotein receptor (LDL-R) transcription in liver cells.