• 元素周期表.XlSX (55.5KB) X   Periodic table of the innovation

    Chemical Element ZXY Axis Electronic Arrangement Table Tabulation principle: Please refer to the ACS network "An open letter to chemists "
    Ruishi Fang
    last modified by Ruishi Fang
  • An Open Letter to the Chemists.doc

    Chemical theoretical innovation
    Ruishi Fang
    last modified by Ruishi Fang
  • Application of Fragment Libraries in Drug Discovery

    As an efficient method to accelerate the process of drug discovery, fragment screening has been widely recognized in academic and commercial fields. The FBDD method usually first determines the affinity of a water-sol...
    Alex Dean
    created by Alex Dean
  • High-throughput Screening

    High-throughput screening technology is a method for screening candidate drugs that interact with targets from a large number of drug samples by using microplates containing molecules (such as enzymes and receptors) a...
    Alex Dean
    created by Alex Dean
  • API Synthesis

    Active Pharmaceutical Ingredient (API) is defined by U.S. Food & Drug Administration as: any substance or mixture of substances intended to be used as the active ingredient in the manufacture of a drug (medicinal)...
    Alex Dean
    created by Alex Dean
  • What Is Medicinal Chemistry?

    Medicinal chemistry is an integrated discipline which links many scientific fields in researching and developing new drugs. Medicinal chemistry deals with the design, optimization and development of chemical compounds...
    Alex Dean
    created by Alex Dean
  • Role of Screening Libraries in Drug Discovery

    Screening libraries play a central role in modern drug discovery. They can be used to help produce new, pharmaceutical and lead-based screening compounds based on drug discovery in the ever-changing demands of industr...
    Alex Dean
    created by Alex Dean
  • Application of Peptide PEGylation

    PEGylation of peptides has proven to be useful for several applications:  > PEGylation at cysteine residue> Arginine modification> Carboxyl group modification> Hydroxyl group conjugation> Acti...
    Cathy Miller
    created by Cathy Miller
  • NHS-Activated Peptide Conjugation Magnetic Beads

    NHS-Activated Peptide Conjugation Magnetic Beads, also called immunomagnetic microspheres, is a small spherical particle with superparamagnetic and protective shell, which is basically composed of carrier microspheres...
    Cathy Miller
    created by Cathy Miller
  • Application of Peptides-Metal Chelates Conjugation

    Application of Peptides-Metal Chelates Conjugation For molecular imaging Molecular imaging has become an indispensable tool in modern diagnostics in biomedical research and therapeutic fields. Cancer cells that expres...
    Cathy Miller
    created by Cathy Miller
  • Preparation of peptide and oligonucleotide conjugates

    Preparation of Peptide-oligonucleotide Conjugation There are several different strategies for synthesizing peptide and oligonucleotide conjugates, including solid phase synthesis, liquid phase synthesis, and biosynthe...
    Cathy Miller
    created by Cathy Miller
  • Peptide Tags

    Peptide TagsFlag tag Flag tag (DYKDDDDK) is a common, well-characterized hydrophilic tag. It is always used in conjunction with antibodies in protein pull-downs to study protein interactions. Flag tag can be incorpora...
    Cathy Miller
    created by Cathy Miller
  • Peptides-Carraier Protein Conjugation

    Type of Peptides-Carraier Protein Conjugation For immunological reasons, the choice for carrier proteins usually ends at bovine serum albumin (BSA), ovalbumin (OVA), or keyhole limpet hemocyanin (KLH): When the cost i...
    Cathy Miller
    created by Cathy Miller
  • Peptide Spin Labels

    Peptide Spin Labels Spin labeling refers to a chemical technique that integrates molecules containing unpaired electrons into another research framework. For the study of biomacromolecule structure, kinetics and confo...
    Cathy Miller
    created by Cathy Miller
  • Application of Cross Linkers

    Cross-linkers are used to determine the relationship between adjacent proteins as well as ligand-receptor interactions. Photo-reactive crosslinkers are widely used for nonspecific bioconjugation. While numerous option...
    Cathy Miller
    created by Cathy Miller
  • Stearoyl-CoA Desaturase Inhibitor  and Diseases

    Stearoyl-CoA Desaturase inhibitor (SCD) and diseases In order to adapt to the rapid development of modern life, reduced physical activity and increased energy intake has led to the onset of obesity , and obesity exac...
    Alex Dean
    created by Alex Dean
  • Inhibition of Sphingosine 1 Phosphate Receptor Inhibitor

    Sphingosine 1 phosphate receptor (S1PR) is a member of the G protein-coupled receptor (GPCR) family, which is mainly coupled with the G protein α subtype. Numerous studies in recent years have yielded a vari...
    Alex Dean
    created by Alex Dean
  • Vesicular monoamine transporter 2 Inhibitor

    Methamphetamine abuse escalates, but no approved therapeutics are available to treat addicted individuals. Methamphetamine increases extracellular dopamine in reward-relevant pathways by interacting at vesicular monoa...
    Alex Dean
    created by Alex Dean
  • Tau Fragments

    Fibers of fragments from the microtubule binding domain had a cross β-structure that closely resembles that reported both for neurofibrillary tangles found in Alzheimer's disease brain and for fibrous lesions fro...
    Cathy Miller
    created by Cathy Miller
  • Diversity of Human Insulin-like Growth Factor (IGF) Binding Protein-2 Fragments

    The insulin-like growth factor binding proteins (IGFBPs) play a major role in the regulation of the effects and the bioavailability of the insulin-like growth factors (IGFs). IGFs are released from IGFBP−IGF com...
    Cathy Miller
    created by Cathy Miller