• galvanic action in building science

    I have come into conflicting information regarding galvanic action as it applies to dissimilar metals.  As I understand it the anode is negative and the electric current flows from the negative to the positive ca...
    banyan sy
    last modified by banyan sy
  • Recent Updates to the Polymer Science Learning Center

    The Polymer Science Learning Center began life with NSF funding in the early to mid '90's. That generous support allowed development of the Macrogalleria, an online resource with hundreds of pages of information on po...
    Lon Mathias
    created by Lon Mathias
  • Mendeleev's periodic table

    This is a two-part question regarding Mendeleev’s periodic table of 1869:   If fluorine was discovered in 1886, why is it shown in Mendeleev’s periodic table of 1869? If terbium was discovered in 18...
    Jaime Aguirre
    created by Jaime Aguirre
  • Migrating .sites Websites

    The ACS Website Team is giving excellent advice to Sections, Divisions, and other ACS entities, for creating new websites for themselves that are independent of the sites.acs.org platform which, for reasons beyond ACS...
    Paul Tukey
    last modified by Paul Tukey
  • Want to add something to a spreadsheet? Leave your suggestions here!

    These spreadsheets are compilations of resources that component groups in the past have found to be of value. If you have your own resources that you would like to share with others, please let us know and we may add ...
    Jamie Heinrich
    last modified by Jamie Heinrich
  • Lead Optimization in Discovery Drug Metabolism and Pharmacokinetics

    Lead optimization using drug metabolism and pharmacokinetics (DMPK) parameters has become one of the primary focuses of research organizations involved in drug discovery in the last decade. Using a combination of rapi...
    Alex Dean
    created by Alex Dean
  • Computer-aided drug discovery and development

    Computer Aided Drug Discovery   Computer-aided approaches have been widely used in pharmaceutical research to improve the efficiency of the drug discovery and development pipeline. To identify and design small m...
    Alex Dean
    created by Alex Dean
  • Fragment-based lead discovery

    Fragment-based lead discovery is gaining momentum in both large pharmaceutical companies and biotechnology laboratories as a complementary approach to traditional screening. This is because fragment-based approaches r...
    Alex Dean
    created by Alex Dean
  • Overview of high-throughput screening

    High-throughput screening (HTS) is a key process used in drug discovery to identify hits from compound libraries that may become leads for medicinal chemistry optimization. This updated overview discusses the utilizat...
    Alex Dean
    created by Alex Dean
  • Design Principles for Fragment Libraries

    Fragment Libraries Fragment-based drug discovery (FBDD) is well suited for discovering both drug leads and chemical probes of protein function; it can cover broad swaths of chemical space and allows the use of creati...
    Alex Dean
    created by Alex Dean
  • Drug screening

    Screening libraries play a central role in modern drug discovery. They can be used to help produce new, pharmaceutical and lead-based screening compounds based on drug discovery in the ever-changing demands of industr...
    Alex Dean
    created by Alex Dean
  • Introduction to Pharmaceutical Chemistry

    Pharmaceutical chemistry is the study of drugs, and it involves drug development. This includes drug discovery, delivery, absorption, metabolism, and more. There are elements of biomedical analysis, pharmacology, phar...
    Alex Dean
    created by Alex Dean
  • Improving API Synthesis

    Organic chemists face the ongoing challenge of developing and optimizing a synthesis for active pharmaceutical ingredients (APIs), namely, API synthesis. These challenges involve a multitude of issues designed to impr...
    Alex Dean
    created by Alex Dean
  • The Three Obstacles Stopping Cell Therapy Becoming Mainstream

    Over the last decade, the field of cell therapy has expanded rapidly. However, while there are now more cell therapies on offer than ever before, there are a number of factors that are still preventing them from becom...
    Cathy Miller
    created by Cathy Miller
  • Cancer immunotherapy targeting neoantigens

    Neoantigens are antigens encoded by tumor-specific mutated genes. Studies in the past few years have suggested a key role for neoantigens in cancer immunotherapy. Here we review the discoveries of neoantigens in the p...
    Cathy Miller
    created by Cathy Miller
  • Isotope Labeled Peptides

     How to generate isotope-labeled peptides remains an urgent challenge for accurately quantitative targeted proteomics on a large scale. Herein, we propose that isotope-labeled peptides fused with a quantitative t...
    Cathy Miller
    created by Cathy Miller
  • Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein Cargos

    Cell-penetrating peptides (CPPs) constitute a promising tool and have shown applications for peptide and protein delivery into cells as well as across various epithelia and the blood-brain barrier (BBB). CPP-mediated ...
    Cathy Miller
    created by Cathy Miller
  • Intracellular Targeting Mechanisms by Antimicrobial Peptides

    Antimicrobial peptides (AMPs) are expressed in various living organisms as first-line host defenses against potential harmful encounters in their surroundings. AMPs are short polycationic peptides exhibiting various a...
    Cathy Miller
    created by Cathy Miller
  • Improving Glycopeptide Synthesis:  A Convenient Protocol for the Preparation of β-Glycosylamines and the Synthesis of Glycopeptides

    Glycopeptide Synthesis   Herein we apply a recently introduced protocol using ammonium carbamate in methanol to the amination of crude chitobiose leading to 1,β-aminochitobiose. This simple, one-step proced...
    Cathy Miller
    created by Cathy Miller
  • Leadership

    I just read an interesting article about leadership and chemistry: Can leadership skills elevate scientists & engineers beyond research? EIN Presswire - Philip Abraham - May 14, 2019 07:41 Leadership education w...
    Arlene Garrison
    last modified by Arlene Garrison