Publication Details (including relevant citation information):
Smith, Polina B.; Ewy, Todd R.; Bartholomew, Glenn P. Department of Chemistry, University of Washington, Seattle, WA, USA. Abstracts of Papers, 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009 (2009), ORGN-090.
The performance of the optimized two-photon absorption (TPA) chromophores decreases significantly when switched from an org. to an aq. environment due to the drop in quantum yield and TPA cross section. To gain insight into the reasons for this drop, we have synthesized a series of DSB chromophores with various water-solubilizing groups and studied the effect of these groups on the chromophore's photophys. properties in different solvents. In DMSO, all the chromophores showed comparable performance. However, in water, chromophores derivatized with sugars (mannose and lactose) performed better, giving a higher quantum yield and larger TPA cross section compared to chromophores derivatized with more conventional water-solubilizing groups (PEO and an ionic group). The synthesis and photophys. properties of these chromophores along with a discussion of the obsd. trend will be presented.
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