Masato Ito - Highly Enantioselective Hydrogenative Desymmetrization of Bicyclic Imides Leading to Multiply Functionalized Chiral Cyclic Compounds

Version 1

      Publication Details (including relevant citation   information):

      http://dx.doi.org/10.1021/ja105048c

      Abstract:

      Highly enantioselective hydrogenative desymmetrization of   bicyclic imides has been developed with chiral Cp*Ru(PN)   catalysts. The present hydrogenation directly provides   stereochemically well-defined cyclic compounds with excellent   enantiomeric exessses, which might otherwise require a detour to   reach.

      Address (URL): http://dx.doi.org/10.1021/ja105048c