Richard Cummings - Publications 1.          Ni, Y.G., Condra, J.H., Orsatti, L., Shen, X., Di Marco, S., Pandit, S., Bottomley, M.J., Ruggeri, L., Cummings, R.T., Cubbon, R.M

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      Publication Details (including relevant citation   information): Publications 1. Ni, Y.G., Condra, J.H.,   Orsatti, L., Shen, X., Di Marco, S., Pandit, S., Bottomley, M.J.,   Ruggeri, L., Cummings, R.T., Cubbon, R.M., Santoro, J.C., Fisher,   T.S., Ha, S., Njimuloh, L., Wood, D.D., Hammond, H.A.,   Wisniewski, D., Volpari, C., Noto, A., Lo Surdo, P., Calzetta,   A., Noto, A., Hubbard, B., Carfi, A., Sitlani, A., "A PCSK9   C-terminal Domain Antibody Antigen Binding Fragment Inhibits   PCSK9 Internalization And Restores LDL-uptake." Submitted to J.   Biol Chem. 2. Bottomley, M.J., Cirillo, A., Orsatti, L., Ruggeri,   L., Fisher, T.S., Santoro, J.C., Cummings, R.T., Cubbon, R.M., Lo   Surdo, P., Calzetta, A., Noto, A., Baysarowich, J., Mattu, M.,   Talamo, F., De Francesco, R., Sparrow, C.P., Sitlani, A., Carfi,   A., "Structural and Biochemical Characterization of the Wild Type   PCSK9-EGF(AB) Complex and Natural Familial Hypercholesterolemia   Mutants." J. Biol Chem., 2009, 284(2):1313-23. 3. Pandit, S.,   Wisniewski, D., Santoro, J.C., Ha, S., Ramakrishnan, V., Cubbon,   R.M., Cummings, R.T., Wright, S.D., Sparrow, C.P., Sitlani, A.,   Fisher, T.S., "Functional analysis of sites within PCSK9   responsible for hypercholesterolemia.", J Lipid Res., 2008,   49(6),1333-43. 4. Parthasarathy, G., Cummings, R., Becker, J.W.,   Soisson, S.M.., " Surface-entropy reduction approaches to   manipulate crystal forms of beta-ketoacyl acyl carrier protein   synthase II from Streptococcus pneumoniae.", Acta Crystallogr D   Biol Crystallogr., 2008, 64(Pt 2):141-8. 5. Fisher, T.S., Lo   Surdo, P., Pandit, S., Mattu, M., Santoro, J.C., Wisniewski, D.,   Cummings, R.T., Calzetta, A., Cubbon, R.M., Fischer, P.A.,   Tarachandani, A., De Francesco, R., Wright, S.D., Sparrow, C.P.,   Carfi, A., Sitlani, A., "Effects of pH and low density   lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation." J   Biol Chem., 2007, 282(28), 20502-12. 6. Jayasuriya, H., Herath,   K.B., Zhang, C., Zink. D.L., Basilio, A., Genilloud, O., Diez,   M.T., Vicente, F., Gonzalez, I., Salazar, O., Pela

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