Publication Details (including relevant citation information):
Critical Reviews in Toxicology 27(3), 253-259 (1997)
Occupational exposure to inorganic acidmist containing sulfuric acid has been associated withincreased laryngeal cancer. Several chronic toxicity studies had exposures of 1 year or longer. No evidence from experimental animals strongly supports or refutes the induction of cancer by inorganic acid mists. Possible mechanism associated with carcinogenicity may relate to lowering of pH; reduced pH can induce chromosomal aberrations, enhance depurination and deamination of cytidine in DNA. This maechanism has not been evaluated in tissues of the respiratory tract.
Address (URL): http://