Publication Details (including relevant citation information):
International application WO/2003/080587, 02 October 2003 (priority date 21 March 2002)
There are provided stable labelled taxanes, characterized in that the isotopes are present in the benzoyloxy group at the C-2 position. More particularly, one or more of the hydrogen or carbon atoms of the benzoyl residue at the C-2 position of the taxane skeleton is replaced respectively from deuterium or 13C. A process for their preparation and their use as internal standard in analytical methods for determining taxanes, useful anticancer drugs, are also provided.
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