Selwyn Yorke - 2-Acetamido-1,2-dideoxynojirimycin: an improved synthesis

Document created by Selwyn Yorke on Aug 22, 2014
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  Publication Details (including relevant citation   information):

  Tetrahedron (1993), 49(42), 9605-12

  Abstract:

  The potent .beta.-N-acetylglucosaminidase inhibitor,   2-acetamido-1,2-dideoxynojirimycin, was prepd. in 6 steps from   N-acetyl-D-glucosamine (overall yield 10%) via the double   reductive amination of a keto aldehyde as the key step.

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