Publication Details (including relevant citation information):
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1991), (1), 85-8
Aristolindiquinone, (I) was prepd. by the addn. of 1-methoxy-1-trimethylsiloxypenta-1,3-diene to 5-bromo-2-methoxy-3-methyl-1,4-benzoquinone. 2,8-Dihydroxy-3,5-dimethyl-1,4-naphthoquinone was prepd. by reaction of the same diene with 2-methoxy-3-methyl-1,4-benzoquinone. The reaction readily provided sufficient quantities of I for biol. evaluation of fertility regulation in rats, for which purpose it was found to be inactive.
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