Selwyn Yorke - A procedure for the analysis of glycosaminoglycan mixtures based on digestion by specific enzymes

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  Publication Details (including relevant citation   information):

  Carbohydrate Research (1994), 255, 285-93


  The present paper describes a method of anal. of   glycosaminoglycan (GAG) mixts. utilizing selective enzymes to   digest specific components of GAG mixts. which is rapid, robust,   and suitable for use in an industrial setting.  The use of   enzymes gives a selectivity for the different GAG species which   is not available by any chem. means.  In conjunction with   electrophoresis and NMR, the method allows the detn. of   chondroitin sulfate-like regions within dermatan sulfate polymers   and, to some extent, their distribution.

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