J Michael Sauder - Genomic fold assignment and rational modeling of proteins of biological interest

Version 1

      Publication Details (including relevant citation   information):

      Proc Int Conf ISMB (2000) 8: 296-306.

      Sauder JM, Dunbrack RL Jr

      Abstract:

      The first available genome of a multicellular organism, C.   elegans, was  used as a test case for protein fold   assignment using PSI-BLAST,  followed by rational structure   modeling and interpretation of  experimental mutagenesis   data in the context of collaboration with  biologists.   Similar results are demonstrated for human disease proteins    with known polymorphisms.

      Address (URL): http://www.ncbi.nlm.nih.gov/pubmed/10977091