Vasudeva Sagi - Enantio- and Diastereocontrolled Total Synthesis of (+)-Boronolide

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  Publication Details (including relevant citation   information):

  J. Org. Chem. 2006, 71,   3935-3941


  An efficient stereoselective total synthesis of (+)-boronolide   from valeraldehyde is described. The key steps include a   Sharpless asymmetric hydroxylation, a chelation-controlled vinyl   Grignard reaction followed by a Sharpless asymmetric epoxidation,   hydrolytic kinetic resolution, and a ring-closing metathesis.

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