Publication Details (including relevant citation information):
Journal of Chemistry and Chemical Engineering, Vol.4, No.7, 2010, PP 39-45
Batch and continuous fermentation of gluconic acid production has been studied. The kinetic parameters of the fermentation process were determined from the batch experimental data. The continuous fermentation was modeled to be carried out in a stirred tank reactor. The effect of hydraulic retention time on the steady state continuous fermentation process of glucose by Aspergillus niger to produce gluconic acid was investigated. The result showed that increasing the hydraulic retention time caused the cell amount and gluconic acid concentration at the outlet stream increased but the glucose concentration at the outlet stream decreased. The steady state simulation result was useful for fermenter size determination. Dynamic behaviour of gluconic acid production through fermentation by Aspergillus niger was also studied for a fermenter with 24 h hydraulic retention time. Applying step change of inlet substrate concentration resulted in first order response of cell, substrate and product concentration with all having positive gain. On the other hand, applying step change of inlet cell concentration has resulted in positive gain for cell and product concentration and negative gain for substrate concentration with first order response for all those three parameters.