Deniz Yuksel - Bioorthogonal Noncovalent Chemistry: Fluorous Phases in Chemical Biology

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  Publication Details (including relevant citation   information):

  Yoder, N.C.; Yuksel, D.; Dafik, L.; Kumar, K.   Curr. Opin. Chem. Biol. 2006, 10,   576-583.

 

  Abstract:

  Chemical entities designed to noncovalently interact with
  predetermined partners have fashioned a new paradigm in
  chemical biology. Fluorocarbons are extremely promising as
  supramolecular synthons toward these objectives.
  Bioorthogonal noncovalent interactions provide a way to
  modulate self-assembled systems in environments where such
  control has hitherto not been possible. Fluorocarbons have
  now found applications in self-assembly as well as   proteomics,
  biomolecule purification and in the creation of microarray
  platforms. Other self-assembly motifs with similar attributes
  might be exploited using the same general approach.

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