Publication Details (including relevant citation information):
Blakey, I.; Day, G.; Girjes, E.; Hunter, D. S.; Rasoul, F., Polymer International 2003, 52 (11), 1734-1739.
A series of \"pellicular\" type supports were fabricated by direct gamma-radiation-mediated graft polymn. of styrene onto polypropylene, followed by aminomethylation. Raman spectroscopy was used for measuring the level of penetration of polystyrene graft into polypropylene, and other structural features such as d. of graft and depth of functionalisation. The kinetics of the coupling of fluorenylmethylcarbamate (Fmoc)-labeled amino acids, to the aminomethylated polystyrene grafts have been measured by UV absorption followed cleavage of the Fmoc chromophore. The Raman spectroscopy results showed that for this series of expts. the calcd. rate coeff. for coupling of Fmoc-labeled amino acids was primarily dependent on graft thickness, but was also influenced by the proportion of polystyrene graft to polypropylene. In general, it was also shown that with increasing loading capacity of support the calcd. rate coeff. for amino-acid coupling decreased correspondingly. In addn., a support that had both a high rate coeff. and a high loading capacity was prepd. from polypropylene base material with a co-continuous porous structure (high surface area).
Address (URL): http://onlinelibrary.wiley.com/doi/10.1002/pi.1300/abstract?