Cory Hawkins - Understanding Split Peaks

Document created by Cory Hawkins on Aug 22, 2014
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  Publication Details (including relevant citation   information):

  C.A. Hawkins and J.W. Dolan, Understanding Split Peaks,   LC/GC, 21 (12) 1134-1138, 2003


  Peak   splitting in a liquid chromatography

  (LC)   separation results from several

  problems. This   month’s “LC Troubleshooting”

  looks   at several possible causes of peak

  splitting and   presents some guidelines for

  isolating the   source of peak splitting.

  Because some   instances of peak splitting

  can be   indicative of method problems that

  should   be corrected, it is important to

  isolate the   problem source carefully, if at all

  possible, so you   can make method changes

  and   avoid or delay future problems. In the

  end,   your method will be more rugged.

  Address (URL): urope/042004/82562/article.pdf