Idriss Blakey - Biomimetic Surface Modification of Honeycomb Films via a "Grafting From" Approach.

Version 1

      Publication Details (including relevant citation   information):

      Nystrom, D.; Malmstroem, E.; Hult, A.; Blakey, I.; Boyer, C.;   Davis, T. P.; Whittaker, M. R., Langmuir 2010, 26 (15),   12748-12754.

      DOI: 10.1021/la1011567


      Hydrophobic isoporous membranes were fabricated using the   “breath  figure” method from polystyrene stars synthesized   via ATRP. The living  polymer chain ends at the surface of   the films were then used, without  further modification, in   a “grafting-from” approach to grow  surface-linked   polyglycidyl methacrylate chains under conditions that    maintained the regular honeycomb structure. This versatile   functional  surface was then used as a platform to build a   small library of surfaces  using a variety of simple   chemistries: (i) the acid hydrolysis of the  epoxide to form   bis-alcohol groups and (ii) utilizing the “click-like”    epoxide−amine reaction to functionalize the surface with a   model  biomolecule—(biotinamido)pentylamine. The successful   modifications were  confirmed by a combination of   spectroscopic and biological means.  Changes in the growth   characteristics of nonmotile Psychrobacter sp. strain,   SW5, on the honeycomb films, provided further evidence    confirming changes in the hydrophobicity of the surface upon   grafting.

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