Lee Hoffman - New Insights into the Structure of PAMAM Dendrimer/Gold Nanoparticle Nanocomposites 

Version 1

      Publication Details (including relevant citation   information):

      Langmuir, 2011, 27 (11), pp 6759–6767

      DOI: 10.1021/la1050964


      In this work, we have employed a suite of complementary   analytical techniques to shed light on the nanocomposite   structures formed during gold nanoparticles (AuNPs) synthesis in   the presence of poly(amidoamine) (PAMAM) dendrimers.   Nanocomposites of AuNPs and either fourth or eighth generation   amine-terminated PAMAM dendrimers (G4 or G8) were prepared. The   size distributions of AuNPs and the nanocomposites were   determined by transmission electron microscopy. Atomic force   microscopy phase imaging and neutral impact collision ion   scattering spectroscopy (NICISS) were utilized for the first time   to investigate and compare nanocomposite structures formed from   G4 and G8. Our results suggest that G4 stabilized the AuNP by   capping the AuNP particle surface but that a certain fraction of   the gold surface was still barely covered. In contrast, the metal   nanoparticle surface was completely covered by G8. In addition,   NICISS results provided evidence that nanocomposites deformed   when being deposited directly onto a substrate.

      Address (URL): http://pubs.acs.org/doi/abs/10.1021/la1050964