Kelly Stewart - Cyanine Dye Conjugates as Probes for Live Cell Imaging

Document created by Kelly Stewart on Aug 22, 2014
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  Publication Details (including relevant citation   information):

  J.R.Carreon,   K.M. Stewart,   K.P. Mahon, S. Shin, and S.O. Kelley, Bioorg. Med. Chem.   Lett. 200717, 5182


  A series of fluorescent compounds suitable for live cell imaging   is described. Functionalized forms of four different asymmetric   cyanine dyes are reported that are amenable to peptide   conjugation. The photophysical properties of the modified dyes   and conjugates and the use of the compounds as cellular imaging   agents are described. The results obtained indicate that these   spectrally versatile compounds, which have absorption and   emission profiles spanning the visible spectrum, are useful   probes for cellular imaging.

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