Christophe Grosjean - Catalytic, asymmetric Strecker reactions catalysed by titaniumIV and vanadiumV(salen) complexes

Document created by Christophe Grosjean on Aug 22, 2014
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  Publication Details (including relevant citation   information):

  Blacker, J.; Clutterbuck, L. A.; Crampton, M. R.; Grosjean, C.;   North, M. Tet. Asymmetry, 2006,   17, 1449‐1456


  VanadiumV(salen) complex 3 has been found to be an effective   catalyst for the asymmetric addition of hydrogen cyanide   (generated

  in situ from trimethylsilyl cyanide) to imines. The best results   (up to 81% enantiomeric excess) were obtained for aromatic imines

  in which the nitrogen atom is protected with a benzyl group and   in which the imine bond is not sterically encumbered.

  Address (URL): 24739&_coverDate=05%2F15%2F2006&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway & _sort=d&_docanchor=&view=c&_acct=C000014659&_version=1&_urlVersion=0&_userid=22 4 739&md5=79fe4c34d5c734aacdbc7abc649c01fc&searchtype=a