Publication Details (including relevant citation information):
Author(s): Bajwa N, Jennings MP
Source: JOURNAL OF ORGANIC
CHEMISTRY Volume: 73 Issue: 9 Pages: 3638-3641 Published: MAY 2 2008
Times Cited: 0
In this paper, we have demonstrated that Red-Al is an efficient chelation-controlled reducing reagent for acyclic acetal (i.e., MOM, MEM, SEM, and BOM) protected alpha-hydroxy ketones. Typically, diastereomeric ratios (dr) ranged from 5 to 20:1 for the 1,2-anti-diols in good to excellent yields.
Address (URL): http://pubs.acs.org/doi/full/10.1021/jo800150x