Timothy Ramadhar - BATE-LACTAMASE INHIBITORS

Document created by Timothy Ramadhar on Aug 22, 2014
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  Publication Details (including relevant citation   information):

  Gary I. Dmitrienko, Jarrod W. Johnson, Timothy R. Ramadhar,   Thammaiah Viswanatha, Sundaramma Viswanatha. United States Patent   Application Publication Filed March 17, 2008 Published February   24, 2011.

  Abstract:

  The present invention relates to broad spectrum β-lactamase   inhibitors. More particularly, the invention relates to   inhibitors of Class B metallo (MBL) and Class D (OXA)   β-lactamases. A method of treating a bacterial infection is   provided, wherein the method comprises administering to a   mammalian patient in need of such treatment a compound of formula   (I) ##STR00001## wherein R.sub.1 is selected from ##STR00002##   R.sub.2 is selected from ##STR00003## with certain provisos as   herein defined; in combination with a pharmaceutically acceptable   β-lactam antibiotic in an amount which is effective for treating   the bacterial infection.

  Address (URL): http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u= %2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220110046101%22.PGNR.&OS=DN/2 0110046101&RS=DN/20110046101

 

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