Publication Details (including relevant citation information):
Dmitry Tsvelikhovsky and Stephen L. Buchwald
J. Am. Chem. Soc., 2010, 132 (40), pp 14048–14051
Publication Date (Web): September 21, 2010 (Communication)
The Pd-catalyzed condensation of 2-bromostyrene and 2-chloroaniline derivatives yields stable diphenylamine intermediates, which are selectively converted to five-, six-, or seven-membered heteroaromatics (indoles, carbazoles, acridines, and dibenzazepines). The selectivity of these intramolecular transformations is uniquely ligand-controlled and offers efficient routes to four important classes of heterocycles from a common precursor.
Address (URL): http://pubs.acs.org/doi/pdf/10.1021/ja107511g