Sandeep Kumar Vashist - Delivery of drugs and biomolecules using carbon nanotubes

Document created by Sandeep Kumar Vashist on Aug 22, 2014
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  Publication Details (including relevant citation   information):

    CARBON,   49(13), 4077-97.    2011


  Carbon nanotubes (CNTs) have emerged as one of the most advanced   nanovectors for the highly efficient delivery of drugs and   biomolecules. They offer several appealing features such as large   surface areas with well defined physico-chemical properties as   well as unique optical and electrical properties. They can be   conjugated non-covalently or covalently with drugs, biomolecules   and nanoparticles. Albeit some pending concerns about their   toxicity in vitro and in vivo, functionalized   CNTs appear to exhibit very low toxicity and are not immunogenic.   Thus, they could be promising carriers with a great potential for   the development of a new-generation delivery system for drugs and   biomolecules. There have been significant advances in the field   of CNT-based drug delivery, especially in the specific targeting   of anticancer and anti-inflammatory drugs for tissues and organs   in the body, where their therapeutic effect is highly required.   Other promising applications are the delivery of DNA, RNA and   proteins.

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