Tathagata Mukherjee - CuO Nanoparticles Catalyzed C−N, C−O, and C−S Cross-Coupling Reactions: Scope and Mechanism

Version 1

      Publication Details (including relevant citation   information):

      J. Org. Chem.,  2009, 74 (5), pp 1971–1976

      Publication Date (Web): January 27, 2009   (Article)

      DOI: 10.1021/jo8024253


      CuO nanoparticles have been studied for C-N, C-O, and C-S bond   formations via cross-coupling

      reactions of nitrogen, oxygen, and sulfur nucleophiles with aryl   halides. Amides, amines, imidazoles,

      phenols, alcohols and thiols undergo reactions with aryl iodides   in the presence of a base such as KOH, Cs2CO3, and K2CO3 at   moderate temperature. The procedure is simple, general,   ligand-free, and efficient to afford the cross-coupled products   in high yield.

      Address (URL): http://pubs.acs.org/doi/pdf/10.1021/jo8024253