Dineshkumar Manvar - Synthesis and structural conformation of N-substituted 1,4-dihyropyridine derivatives

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      Publication Details (including relevant citation   information):

      Crystal Research and Technology, 2006, 41 (1), 92-97

      Abstract:

      N-(Phenyl)-3,5-dicarbethoxy-2,6-dimethyl-4-(phenyl)-1,4-dihydropyridine   (A) and N-(4-methoxy phenyl)-3,5 dicarbethoxy-2,6   dimethyl-4-(3-nitro phenyl)-1,4-dihydropyridine (B) has been   synthesized as per scheme and characterized by the X-ray   diffraction method. The compound A crystallizes in monoclinic   space group P21/c with cell parameters a = 9.2770(11)A, b =   8.6410(5)A, c = 27.601(3)A, β = 97.724(3)°, Z = 4. The compound B   crystallizes in monoclinic space group P21/c with cell parameters   a = 11.229(6), b = 12.746(7)A, c =17.606(6)A, β = 104.531(3)°, Z   = 4. The structures exhibit both intra and intermolecular   hydrogen bonds. Dihydropyridine ring of both the compounds adopt   a flat boat conformation.

      Address (URL): http://onlinelibrary.wiley.com/doi/10.1002/crat.200310539/abstract