Steven Meyers - Endothelialization of Titanium Surfaces

Document created by Steven Meyers on Aug 22, 2014
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  Publication Details (including relevant citation   information):

  Meyers, S., Hamilton, P., Walsh, E., Kenan, D. and Grinstaff, M.   (2007). Advanced Materials, 19: 2492–2498. doi:   10.1002/adma.200700029


  An interfacial peptide coating possessing domains that bind to Ti   and endothelial cells is synthesized (see figure). Peptides with   specific adherence to Ti are identified using phage display, and   the RGD motif was selected for cell binding. The peptide can be   applied from aqueous solution and possesses micromolar binding   affinities. The coating significantly enhances endothelial cell   adhesion and spreading under both static and dynamic conditions.

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