Suntara Fueangfung - Synthetic oligodeoxynucleotide purification by polymerization of failure sequences

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  Publication Details (including relevant citation   information):

  Shiyue Fang*, Suntara Fueangfung, Xi Lin, Xiang   Zhang, Wenpeng Mai, Lanrong Bi and Sarah A. Green Chem.   Commun., 2011,

  47, 1345-1347 DOI: 10.1039/C0CC04374E ,   Communication


  Synthetic oligodeoxynucleotide is purified by capping failure   sequences with an acrylated phosphoramidite followed by   polymerization and product extraction. The method is suitable for   large scale oligonucleotide drug purification

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