Ivan Kempson - One-pot Tuning of Au Nucleation and Growth: From Nanoclusters to Nanoparticles

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      Publication Details (including relevant citation   information):

      SF Lai, WC   Chen, CL Wang, HH Chen, ST Chen, CC Chien, YY Chen, WT Hung, X   Cai, E Li, IM Kempson, Y Hwu, CS Yang, ES Tok, HR Tan, M Lin, G   Margaritondo, One-pot Tuning of Au Nucleation and Growth: From   Nanoclusters to Nanoparticles, Langmuir,   27,8424-8429, 2011.


      We describe a simple and effective method to obtain colloidal   surface-functionalized Au nanoparticles. The method is primarily   based on irradiation of a gold solution with high-flux X-rays   from a synchrotron source in the presence of   11-mercaptoundecanoic acid (MUA). Extensive tests of the products   demonstrated high colloidal density as well as excellent   stability, shelf life, and biocompatibility. Specific tests with   X-ray diffraction, UVvisible spectrometry, visible microscopy,   Fourier transform infrared spectroscopy, dark-field visible-light   scattering microscopy, and transmission electron microscopy   demonstrated that MUA, being an effective surfactant, not only   allows tunable size control of the nanoparticles, but also   facilitates functionalization. The nanoparticle sizes were 6.45 (   1.58, 1.83 ( 1.21, 1.52 ( 0.37 and 1.18 ( 0.26 nm with no MUA and   with MUA-to-Au ratios of 1:2, 1:1, and 3:1. The MUA additionally   enabled functionalization with L-glycine. We thus demonstrated   flexibility in controlling the nanoparticle size over a large   range with narrow size distribution.

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