Danilo Giribone - Synthesis of Exemestane labelled with 13C

Version 1

      Publication Details (including relevant citation   information):

      E.Fontana, A.Pignatti,   D.Giribone, E.Di Salle

      Steroids, 73 (2008) 760-764

      Abstract:

      The synthesis of exemestane (Aromasin®), an   irreversible steroidal aromatase inhibitor, specifically labelled   with 13C is reported. The preparation of   [13C3]exemestane was achieved according to   an eight-step procedure starting from the commercially available   testosterone.

      Address (URL): http://www.sciencedirect.com/science/article/pii/S0039128X08000846