Elizabeth Crew - Bacterial inactivation using silver-coated magnetic nanoparticles as functional antimicrobial agents

Document created by Elizabeth Crew on Aug 22, 2014
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  Publication Details (including relevant citation   information):

  L. Wang, J. Luo,   S. Shan, E.   Crew, J. Yin, Wallek, S. Wong, C.J. Zhong, “Bacterial   inactivation using silver-coated magnetic nanoparticles as   functional antimicrobial agents”, Anal. Chem.,   2011, 83, 8688–8695.


  The ability for silver nanoparticles to function as

  an antibacterial agent while being separable from the target

  fluids is important for bacterial inactivation in biological   fluids.

  This report describes the analysis of the antimicrobial   activities

  of silver-coated magnetic nanoparticles synthesized by wet

  chemical methods. The bacterial inactivation of several types

  of bacteria was analyzed, including Gram-positive bacteria

  (Staphylococcus aureus and Bacillus cereus) and Gram-negative

  bacteria (Pseudomonas aeruginosa, Enterobacter cloacae, and

  Escherichia coli). The results have demonstrated the viability

  of the silver-coated magnetic nanoparticles for achieving   effective bacterial inactivation efficiency comparable to and   better than that

  of silver nanoparticles conventionally used. The bacteria   inactivation efficiency of our silver-coated MnZn ferrite   (MZF@Ag)

  nanoparticles was also determined for blood platelets samples,   demonstrating the potential of utilization in inactivating   bacterial

  growth in platelets prior to transfusion to ensure blood product   safety, which also has important implications for enabling the

  capability of effective separation, delivery, and targeting of   the antibacterial agents.

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