Publication Details (including relevant citation information):
Journal of Organic Chemistry (2007), 72(9), 3340-3352
1,3-Oxazinan-6-ones have been utilized in a series of enolate reactions to produce 5-hydroxy and 5-alkyl-4-substituted-1,3-oxazinan-6-ones with excellent trans diastereoselectivity. Highlighting the versatility of the oxazinanone, a number of transformations were performed to produce a variety of protected N-H and N-methyl α-hydroxy- and α-methyl-β-amino acids.
Address (URL): http://10.1021/jo0700326