Publication Details (including relevant citation information):
N Yapici et al, Org. Lett., 2012, 14 (1), DOI:pp 50–53, 10.1021/ol202816m
The synthesis, characteristics, and biological applications of a series of new rhodamine nitroxide fluorescent probes that enable imaging of hydroxyl radicals (•OH) in living cells are described. These probes are highly selective for •OH in aqueous solution, avoiding interference from other reactive oxygen species (ROS), and they facilitate •OH imaging in biologically active samples. The robust nature of these probes (high specificity and selectivity, and facile synthesis) offer distinct advantages over previous methods for •OH detection.
Address (URL): http://http://pubs.acs.org/doi/abs/10.1021/ol202816m