Ann Newman - Specialized Solid Form Screening Techniques

Document created by Ann Newman on Aug 22, 2014
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  Publication Details (including relevant citation   information):

  A. Newman. Org. Proc. Res. Dev. 2013, 17, 457-471


  Solid form screening is an integral part of many development   plans at various companies and includes polymorph, salt,   cocrystal, amorphous, and amorphous dispersion screens. There are   a number of traditional solvent- and nonsolvent-based methods   that are employed for these screens. Over time, specialized   screens have been developed to deal with difficult molecules and   situations or to push the limits of traditional experiments. This   contribution outlines a variety of specialized screening   approaches for polymorphs, salts, cocrystals, and amorphous   dispersions. Many techniques are amenable to laboratory equipment   and can be incorporated with minimal start-up time, while others   are very specific and will need specialized equipment and/or   expertise.

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