Christopher Lipinski - Solubility in the Design of Combinatorial Libraries

Document created by Christopher Lipinski on Aug 22, 2014
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  Publication Details (including relevant citation   information): Lipinski, Christopher,   2004, pp 407-434

  Abstract: This chapter contains sections titled:   * Introduction * Changes in Compound Synthesis * Changes in   Compound Physical Form * Changes in Compound Distribution *   Solubility, Potency and Permeability Inter-Relationships *   Turbidimetric/Particle Based Solubility * Solids not   Characterized in Early Discovery * DMSO Solubilization in Early   Discovery * Library Design, In-silico – Experimental Divergence *   Conclusion

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