Alexander Pulis - Stereospecific conversion of alcohols into pinacol boronic esters using lithiation–borylation methodology with pinacolborane

Document created by Alexander Pulis on Aug 22, 2014
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  Publication Details (including relevant citation   information):

  Chem.   Commun.   2014, 50, 4053-4055

    DOI: 10.1039/C4CC00993B

    S. Roesner, C. A. Brown, M. Mohiti,   A. P.   Pulis, R.   Rasappan, D. J. Blair, S. Essafi, D. Leonori and V. K.   Aggarwal

  Abstract:

  The   synthesis of primary and secondary pinacol boronic esters via   lithiation-borylation of carbamates and benzoates with   pinacolborane is described. This new protocol enables the highly   selective synthesis of enantioenriched and geometrically defined   boronic esters that cannot otherwise be accessed by alternative   methodologies.

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