Saleesh Kumar Nambalan Sivaraman - Highly Chromic, Proton-Responsive Phenyl Pyrimidones

Version 1

      Publication Details (including relevant citation   information):

     

     
        Authors    

          Jyothi Dhuguru, Chirag Gheewala, NS Saleesh Kumar, James N       Wilson    

     
     

     

     
        Publication date    

          2011/7/26    

     
     

     

     
        Journal name    

          Organic letters    

     
     

     

     
        Volume    

          13    

     
     

     

     
        Issue    

          16    

     
     

     

     
        Pages    

          4188-4191    

     
     

     

     
        Publisher    

          American Chemical Society    

     
     

     

     
        Description    

          Aryl pyrimidones are pharmacologically relevant compounds       whose optical properties have
          only been partially explored. We report the synthesis and       optical characterization of a series
          of aryl-and diaryl-2 (1 H)-pyrimidones. The electronic       transitions of these chromophores are
          modulated by the extent of conjugation between the pendant       phenyl ring and the pyrimidone
          core as well as the presence of electron-donating       auxochromes. Monoprotonation of the
          pyrimidone ring results in large hyperchromic and       bathochromic shifts as well as switching ...   

     

     

     
       
          Total citations      

            Cited by 9     

       
     

      Abstract:

      Address (URL): http://http://pubs.acs.org/doi/abs/10.1021/ol2014945