A consistent model for the origin of life is basis for healthy nutrition and an account of brain function simplifies science

File uploaded by Michael Deans on Mar 26, 2015
Version 1Show Document
  • View in full screen mode

               I'm Michael T Deans, born in London on the 18th of March 1947, I enjoyed country walks with my father, a geologist specializing in volcanic carbonates and mother, a botanist who taught school and technical college students biology. Science masters at Latymer Upper School inspired me with stories of Michael Faraday's and Linus Pauling's achievements. 

                I entered Churchill College Cambridge with good grades in Mathematics, Physics, Chemistry and Economics to read Natural Sciences, including Biochemistry, Cell biology, Chemistry, Crystallography, Ecology, Maths and Physics. During a Physics practical class in 1967, I serendipitously discovered ice crystallizing in liquid nitrogen and proposed a tetragonal, proton ordered structure 'ice It', dismissed for resembling the ice nine, Kurt Vonnegut introduced in his science fiction Cat’s Cradle. Its existence is still unverified.

               Reading an MSc in Biochemistry at University College London, I applied physics to explain biological energy coupling in striated muscle contraction, oxidative phosphorylation and photosynthesis. Cavities (sarcomeres, mitochondria and chloroplasts) resonate with ~4μ infrared laser light in each case. A ferroelectric transition in ice It was the original source, Pi ~ Pi bond energy from hydrolysing ATP replaces it.

               Training in Clinical Biochemistry at Surrey University, I suggested roles for trace elements in active transport, reinterpreting endocrinology. I also proposed that ice It crystallizing in liquid nitrogen during an extreme ice age underwent a ferroelectric transition emitting ~4µ infrared laser light which photo-phosphorylated nucleotides. They polymerized, forming DNA, basis for the origin of life:

                Comparing the binary logic of an IBM 360 computer and an 8K PET with human intelligence led to my suggesting a DNA-protein complex to account for brain function. I wrote a search engine, word processor and graphics package on a Commodore 64 to illustrate it. Anti-parallel β-pleated sheet hairpin histones with alternate A, L, I or V and R or K (P forms a U-bend) bind DNA bases C, G, A or T, mnemonic A LIVe CiGAreTte, c.f. Gramicidin S.            

                 The B-helix unwinds, 21units form a coil and nine coils a 'minion', stacked minions super-coil, explaining chromosome structure better than nucleosome core particles, they're preparative artefacts. Minions enable replication of 1,701 DNA base pairs without making or breaking the double helix. The H-bonds connecting amino acid ω-amines to DNA phosphates oscillate, constituting the 18 hands of biological clocks with time unit ~1.39*10-15 seconds. Natural intelligence has evolved far beyond current computer technology. The H-bonds binding minions together store intellectual information, nerve fibres act as wave-guides


                 The 'Tyger' time-gravity equation in polar coordinates ϴ and Ф:

                        d2ϴ/dt2 = πβ2/2√e ( [1+β]t/τ + [1+β]-t/τ)  and  d2Ф/dt2 = πβ2/2√e ( [1+β]t/τ - [1+β]-t/τ)

were β = 63-9 and e is the base of natural logarithms replaces Einstein’s relativity, causing planes to appear spherical, as counter-intuitive as quantum mechanics. It describes Mendeleev's periodic table using nested polyhedral shells to replace electron orbitals.