Vahid Jabbari - On-line microextraction of moxifloxacin using Fe3O4 nanoparticle-packed in-tube SPME

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      Publication Details (including relevant citation   information):

        RSC Adv.,   2015,5,   57930-57936

      Abstract:

        In the current study, an in-tube solid-phase microextraction   (SPME) approach based on a Fe3O4nanoparticle-packed   tube for microextraction and detection of moxifloxacin has been   reported. In this regard, the Fe3O4 nanoparticles   (NPs) were prepared by a batch synthesis and were introduced into   a stainless steel tube by a syringe. Afterward, a strong magnet   was placed around the tube, so that the Fe3O4 NPs   were retained in the tube and the tube was used in the in-tube   SPME-HPLC for the analysis of moxifloxacin in urine samples.   Sodium dodecyl sulfate (SDS) was used as bridging agent between   the Fe3O4 NPs   and moxifloxacin. The operational conditions such as the uptake   and release times, flow rate and pH of the solution were   investigated and optimized. According to our findings, the linear   range and the detection limit (S/N =   3) were 0.1–5000 and 0.03 μg L−1,   respectively. Simplicity and facile automation, rapid analysis,   high sensitivity, wide linear range, and fully sorbent collection   after analysis are the main advantages of the method.

      Address (URL): 10.1039/C5RA07049J