Publication Details (including relevant citation information):
Calatayud, D G, Lopez-Torres, E, Mendiola, M A, Pastor, C J, Procopio, J R European Journal of Inorganic Chemistry 2005 (21) 4401-4409
Abstract: Redox-related changes in the biological properties of copper bis(thiosemicarbazones) are induced by the backbone of the ligand. To get information about how these changes depend on the structural parameters, three X-ray structures of complexes with different behaviour of the benzil bis(thiosemicarbazone) ligand have been determined. These include two almost planar copper(II) complexes with different grades of deprotonation in the ligand and a ZnII complex in which the ligand acts as a monoanion and a nitrate group is bonded to the metal ion in a square-based pyramid. The changes in the backbone bond lengths agree with the variation in the ionic radius and with the grade of electronic charge delocalisation in the chelate rings; these have consequences for the coordination sphere, allowing the metal to fit slightly better into the ligand cavity, which in turn may affect the complex stability and the redox potential.
Address (URL): ISI:000233297800019