N Sukumar - Network Measures for Chemical Library Design

Document created by N Sukumar on Apr 7, 2016
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  Publication Details (including relevant citation   information):

 

  Drug Development Research   75: 402–411   (2014)

  Abstract:

  In this overview, we examine recent developments in network   approaches to drug design. A brief overview of networks is   followed by a discussion of how chemical similarity networks and   their properties address challenges in drug design. Multiple   methods used to assess or enhance chemical diversity for   early-stage drug discovery are discussed, as well as methods that   can be used for drug repositioning and ligand polypharmacology.

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