Jason Schaff - An HPLC–HR-MS-MS Method for Identification of Anticoagulant Rodenticides in Blood

Version 2

      Publication Details (including relevant citation   information):

    Schaff and Montgomery: An HPLC–HR-MS-MS Method for Identification of Anticoagulant Rodenticides in Blood, J. Analytical Tox, v. 37, pp. 321-325.

      Abstract:

    This paper presents a fully validated method for the qualitative identification of bromadiolone, brodifacoum, coumachlor, coumatetralyl, difenacoum and warfarin in whole blood specimens. Samples are protein precipitated with acetonitrile, processed via solid-phase extraction and analyzed by high-performance liquid chromatography with high resolution tandem mass spectrometric detection. Limits ofdetection were 10 ng/mL or better for all analytes.

      Address (URL):