Jason Schaff - An HPLC–HR-MS-MS Method for Identification of Anticoagulant Rodenticides in Blood

Document created by Jason Schaff on Jun 2, 2016Last modified by Jason Schaff on Jun 2, 2016
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  Publication Details (including relevant citation   information):

Schaff and Montgomery: An HPLC–HR-MS-MS Method for Identification of Anticoagulant Rodenticides in Blood, J. Analytical Tox, v. 37, pp. 321-325.

  Abstract:

This paper presents a fully validated method for the qualitative identification of bromadiolone, brodifacoum, coumachlor, coumatetralyl, difenacoum and warfarin in whole blood specimens. Samples are protein precipitated with acetonitrile, processed via solid-phase extraction and analyzed by high-performance liquid chromatography with high resolution tandem mass spectrometric detection. Limits ofdetection were 10 ng/mL or better for all analytes.

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