Steven Stellman - Alcohol and breast cancer: a cohort study

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      Publication Details (including relevant citation   information):

      Garfinkel, L., Boffetta, P., Stellman, S. D. 17 (6)   686-93-

      Abstract: The relation between alcohol   consumption and several causes of death, including breast cancer,   was examined in a population of 581, 321 women enrolled in a   prospective study in 1959 and followed for 12 years. Women who   drank occasionally had about the same breast cancer mortality   rate as nondrinkers; those who drank one to four drinks per day   had SMRs 7-26% higher; five drinks per day, 1.89; and six or more   drinks per day, 1.65. The two highest-consumption groups' risks   were significantly higher than those of nondrinkers after   multivariate adjustment for several breast cancer risk factors.   Distinctive dose-response relationships were observed for two   known alcohol-related conditions: cirrhosis of the liver and   cancer of the aero-digestive tract, suggesting that results for   other causes are not seriously biased by misclassification of   drinking habits. Death rates from all causes combined were   elevated for drinkers of three or more drinks per day. Whether or   not the association of elevated breast cancer death rates   ultimately turns out to be causal, there is ample reason to   continue to warn the public against excessive drinking.

      Address (URL): http://www.ncbi.nlm.nih.gov/pubmed/3244667