Steven Stellman - Patterns of artificial sweetener use and weight change in an American Cancer Society prospective study

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      Publication Details (including relevant citation   information):

      Stellman, S. D., Garfinkel, L. 11 Suppl 1 85-91-

      Abstract: Extreme obesity and leanness are risk   factors for many types of cancer. An earlier American Cancer   Society study (1959-1972) found a nearly twofold increased risk   for death from all causes in men and women who weighed 40% or   more above average for their age and height, and found elevated   cancer rates as well. A new (1982), ongoing ACS prospective study   of 1.2 million men and women continues to find increased death   rates from all causes and from cancer in the very heavy and the   very lean. Artificial sweetener (AS) use is an important   correlate of relative weight in this population. The relationship   between weight change during the year preceding enrollment and AS   usage was studied in a highly homogeneous subgroup of 78694 women   ages 50-69 years. The percentage of users increased with body   mass index (BMI) and was inversely related to age. Users were   significantly more likely than non-users to gain weight,   regardless of initial BMI. Among those who gained weight, the   average number of lbs gained by AS users was higher (by 0.5-1.5   lb) than the amount gained by non-users. Within the entire   cohort, AS users of both sexes ate chicken, fish and vegetables   significantly more often than did non-users and consumed beef,   butter, white bread, potatoes, ice cream and chocolate   significantly less often, suggesting that our weight change   results are not explicable by differences in food consumption   patterns.

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