Steven Stellman - Nonmalignant respiratory disease mortality among woodworkers participating in the American Cancer Society Cancer Prevention Study-II (CPS-II)

Document created by Steven Stellman on Dec 1, 2016
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  Demers, P. A., Stellman, S. D., Colin, D., Boffetta, P.   34 (3) 238-43-

  Abstract: Nonmalignant respiratory disease   (NMRD) mortality was examined among woodworkers participating in   the American Cancer Society's CPS-II cohort study. During the   6-year prospective follow-up there were 97 NMRD death's among   11,541 men reporting employment in wood-related occupations and   1,338 NMRD deaths among 317,424 men reporting no exposure to wood   dust or wood-related jobs. Relative risks, adjusted for age and   smoking, were calculated using Poisson regression. A small excess   of NMRD was observed among woodworkers. However, the relative   risk was higher among woodworkers who did not report exposure to   wood dust (RR = 1.52, 95% CI = 1.18-1.97) than those who did (RR   = 1.27, 95% CI = 0.91-1.77), and no clear trend with duration of   exposure was observed. An excess of NMRD was observed among   woodworkers reporting exposure to asbestos (RR = 1.59, 95% CI =   0.85-2.96), as well as the small number of woodworkers reporting   exposure to formaldehyde (RR = 1.95, 95% CI = 0.63-6.06), but men   not reporting exposure to these substances also had an excess   risk. Although limited by a short follow-up period and crude   indicators of exposure, the strengths of this analysis were the   ability to compare woodworkers to a similar, healthy population   and to adjust for the effects of smoking. Cohort studies with   better exposure information are needed to examine the role of   occupational exposures among woodworkers in the etiology of   respiratory disease.

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