Steven Stellman - Reported residential pesticide use and breast cancer risk on Long Island, New York

Document created by Steven Stellman on Dec 1, 2016
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  Publication Details (including relevant citation   information):

  Teitelbaum, S. L., Gammon, M. D., Britton, J. A., Neugut, A. I.,   Levin, B., Stellman, S. D. 165 (6) 643-51-

  Abstract: Pesticides, common environmental   exposures, have been examined in relation to breast cancer   primarily in occupational studies or exposure biomarker studies.   No known studies have focused on self-reported residential   pesticide use. The authors investigated the association between   reported lifetime residential pesticide use and breast cancer   risk among women living on Long Island, New York. They conducted   a population-based case-control study of 1,508 women newly   diagnosed with breast cancer between August 1996 and July 1997   and 1,556 randomly selected, age-frequency-matched controls.   Comprehensive residential pesticide use and other risk factors   were assessed by using an in-person, interviewer-administered   questionnaire. Unconditional logistic regression was used to   calculate odds ratios and 95% confidence intervals. Breast cancer   risk was associated with ever lifetime residential pesticide use   (odds ratio = 1.39, 95% confidence interval: 1.15, 1.68).   However, there was no evidence of increasing risk with increasing   lifetime applications. Lawn and garden pesticide use was   associated with breast cancer risk, but there was no dose   response. Little or no association was found for nuisance-pest   pesticides, insect repellents, or products to control lice or   fleas and ticks on pets. This study is the first known to suggest   that self-reported use of residential pesticides may increase   breast cancer risk. Further investigation in other populations is   necessary to confirm these findings.

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