Steven Stellman - Chronic and acute exposures to the world trade center disaster and lower respiratory symptoms: area residents and workers

Document created by Steven Stellman on Dec 1, 2016
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  Publication Details (including relevant citation   information):

  Maslow, C. B., Friedman, S. M., Pillai, P. S., Reibman, J.,   Berger, K. I., Goldring, R., Stellman, S. D., Farfel, M.   102 (6) 1186-94-

  Abstract: OBJECTIVES: We assessed associations   between new-onset (post-September 11, 2001 [9/11]) lower   respiratory symptoms reported on 2 surveys, administered 3 years   apart, and acute and chronic 9/11-related exposures among New   York City World Trade Center-area residents and workers enrolled   in the World Trade Center Health Registry. METHODS: World Trade   Center-area residents and workers were categorized as case   participants or control participants on the basis of lower   respiratory symptoms reported in surveys administered 2 to 3 and   5 to 6 years after 9/11. We created composite exposure scales   after principal components analyses of detailed exposure   histories obtained during face-to-face interviews. We used   multivariate logistic regression models to determine associations   between lower respiratory symptoms and composite exposure scales.   RESULTS: Both acute and chronic exposures to the events of 9/11   were independently associated, often in a dose-dependent manner,   with lower respiratory symptoms among individuals who lived and   worked in the area of the World Trade Center. CONCLUSIONS: Study   findings argue for detailed assessments of exposure during and   after events in the future from which potentially toxic materials   may be released and for rapid interventions to minimize exposures   and screen for potential adverse health effects.

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