Paul Ornstein - Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bi cyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371·HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepres...

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      Publication Details (including relevant citation   information):

      Chappell, Mark D., Li, Renhua, Smith, Stephon C., Dressman, Bruce   A., Tromiczak, Eric G., Tripp, Allie E., Blanco, Maria-Jesus,   Vetman, Tatiana, Quimby, Steven J., Matt, James, Britton, Thomas   C., Fivush, Adam M., Schkeryantz, Jeffrey M., Mayhugh, Daniel,   Erickson, Jon A., Bures, Mark G., Jaramillo, Carlos, Carpintero,   Mercedes, Diego, José Eugenio de, Barberis, Mario,   Garcia-Cerrada, Susana, Soriano, José F., Antonysamy, Stephen,   Atwell, Shane, MacEwan, Iain, Condon, Bradley, Sougias,   Christine, Wang, Jing, Zhang, Aiping, Conners, Kris, Groshong,   Chris, Wasserman, Stephen R., Koss, John W., Witkin, Jeffrey M.,   Li, Xia, Overshiner, Carl, Wafford, Keith A., Seidel, Wesley,   Wang, Xu-Shan, Heinz, Beverly A., Swanson, Steven, Catlow, John   T., Bedwell, David W., Monn, James A., Mitch, Charles H.,   Ornstein, Paul L. Journal of Medicinal Chemistry  2016 59 (24) 10974-10993

      Abstract:

      No abstract available.

      Address (URL): http://dx.doi.org/10.1021/acs.jmedchem.6b01119