Paul Ornstein - Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bi cyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371·HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepres...

Document created by Paul Ornstein on Jan 17, 2017
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  Publication Details (including relevant citation   information):

  Chappell, Mark D., Li, Renhua, Smith, Stephon C., Dressman, Bruce   A., Tromiczak, Eric G., Tripp, Allie E., Blanco, Maria-Jesus,   Vetman, Tatiana, Quimby, Steven J., Matt, James, Britton, Thomas   C., Fivush, Adam M., Schkeryantz, Jeffrey M., Mayhugh, Daniel,   Erickson, Jon A., Bures, Mark G., Jaramillo, Carlos, Carpintero,   Mercedes, Diego, José Eugenio de, Barberis, Mario,   Garcia-Cerrada, Susana, Soriano, José F., Antonysamy, Stephen,   Atwell, Shane, MacEwan, Iain, Condon, Bradley, Sougias,   Christine, Wang, Jing, Zhang, Aiping, Conners, Kris, Groshong,   Chris, Wasserman, Stephen R., Koss, John W., Witkin, Jeffrey M.,   Li, Xia, Overshiner, Carl, Wafford, Keith A., Seidel, Wesley,   Wang, Xu-Shan, Heinz, Beverly A., Swanson, Steven, Catlow, John   T., Bedwell, David W., Monn, James A., Mitch, Charles H.,   Ornstein, Paul L. Journal of Medicinal Chemistry  2016 59 (24) 10974-10993

  Abstract:

  No abstract available.

  Address (URL): http://dx.doi.org/10.1021/acs.jmedchem.6b01119

 

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