Jean-Claude Bunzli - Lanthanide Luminescent Bioprobes (LLBs)

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  Publication Details (including relevant citation   information):

  Bunzli,J.C.G. Chemistry Letters 2009  38 (2) 104-109

  Abstract: Lanthanide luminescent bioprobes   (LLBs) are amongst the most sensitive luminescent probes because   their excited states are long-lived, which allows time-resolved   detection (TRD) of their luminescence, boosting the   signal-to-noise ratio and the sensitivity in addition they are   fairly insensitive to photobleaching since lanthanide ions are   good quenchers of triplet states. Applications of LLBs to   immunoassays, DNA analysis, ligand binding assays, analyte   sensing, and cellular imaging are reviewed. Future developments   in immunohistochemistry, targeting of specific organelles,   lab-on-a-chip technology, and instrumental design are evoked

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